Technetium-99m Labeled Antisense Oligonucleotide-Noninvasive Tumor Imaging in Mice.
Article N° AJ19-1
Conclusion
S-Acetyl-NHS-MAG3 is an efficient bifunctional chelator for 99mTc labeling with oligonucleotides. Using 99mTc labeled antisense probes, malignant tumors with over-expressed oncogene mRNAs may be specifically imaged at an early stage.